tPa, Stroke and Memory

During my thesis, I studied the role of a protease involved in thrombolysis (destruction of blood clot) the tissue-type plasminogen activator (tPA), which is so far the only available treatment for stroke in human (Benchenane et al. Trends Neurosci 2004). But tPA is also capable of cleaving the NR1 sub-unit of the NMDA receptor leading […]

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Oscillations & memory

Memory is fundamental to human life. It allows us to acquire and use information to adapt our behavior in response to experience. Memory is not a unitary concept but is composed of multiple memory types that involve different neuroanatomic structures (Squire, 2004). The memory of facts and events, called declarative memory has been shown to […]

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Karim Benchenane

Full permanent CNRS Researcher (CR1) Currently: Leader of ATIP/Avenir team Memory Oscillations and Brain states at ESPCI ParisTech Research focus: Brain states, oscillation and memory processes AERES evaluation for the project : A+ in Laboratory of Neurobiology – UMR 7637 CNRS ESPCI 2009-2011: Team Navigation, Memory and Aging, in the Laboratory of Neurobiology of Adaptative […]

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Le Prix La Recherche

Karim Benchenane receives in October 2011 the Price « La Recherche en Neurosciences » for his article: Benchenane K. et al. « Coherent theta oscillations and reorganization of spike timing in the hippocampal-prefrontal network upon learning », Neuron 2010 June24;66(6):921-36.

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